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Program of the 2nd INTERNATIONAL SYMPOSIUM ON BRAIN DEATH
(Havana, Cuba)
February 27-March 1, 1996

Abstracts of the Meeting

Dear colleagues:

Since ancient times, man has pondered the mystery of his own death. It seemed that by knowing meaning of the his death, he would be prepared to understand the reason of his life.

Over the centuries people were deemed dead when they stopped breathing and when their hearts stopped beating. But the technological advances provided by civilization enabled artificial substitution of those functions that were considered responsible of setting the limit between life and death. This was documented by French neurologists and neurophysiologists at the end of the 1950's.

The end of the 1960's was also prominent for further advances in this area. The Ad Hoc Committee of the Harvard Medical School proposed, for first time, a new definition of death on neurological grounds. The Harvard's report appeared some months after Christian Barnard's first transplantation of a human heart, in December 1967. The year of 1981 was highlighted by the report of the President's Commission for the Study of Ethical Problems in Medicine and Behavioral Research to define death. The 1980's and the early 1990's were characterized by multi-disciplinary debates. There were still worldwide controversies about a concept of human death on neurological grounds (whole brain, brainstem death and higher brain formulations of death). There was also disagreement on the diagnostic criteria of brain death, whether clinical alone, or clinical and ancillary tests.

This was the scene we faced in 1992, when we convoked colleagues to attend The First International Symposium on Brain Death, held at the International Conference Center, Havana (September 22-25, 1992). Delegates from twenty-one countries attended this sunny city to discuss many controversial issues concerning brain death and related issues.

It was a remarkable Conference. It was seemingly impossible to gather such an impressive number of the most outstanding personalities in the field. Some had previously offered important contributions for the development of the human death concept. Still others, were contributors on philosophical, theological, bioethical, historical and sociological issues regarding brain death. Further, others were skillful specialists trained in the diagnosis of brain death, who were leaders in the establishment of brain death criteria in their respective countries. Scientific discussions in the Havana Conference were enriched by multi- disciplinary approaches where most brain death-related issues were included. Definitely, contradictions were evident in the debates during the Symposium, therefore, the final consensus among delegates was that the subject of brain death was clearly not closed.

One of the most important achievements of the Symposium was the proposal to organize an international group, commission, or network within this field. This proposal was consummated in Buenos Aires, during the last Congress of the International Association of Bioethics (IAB). Under the sponsoring of the IAB, an International Network on the Definition of Death was organized. The tremendous actuality and the inherent transcendence of this problem is beyond any doubt.

We are pleased to announce the holding of the "II INTERNATIONAL SYMPOSIUM ON BRAIN DEATH, at the Havana International Conference Center, from February 27 to March 1, 1996. Along with the Symposium will be held the "First Meeting of the Network on the Definition of Death" of the International Association of Bioethics, and the "V International Meeting of the Quantified Neurophysiology Belgian Group".

The Proceedings of the Symposium will be published by Elsevier Science, B. V. in a 300-page book that is already in press. It will available at the Symposium with key note lectures on these issues.

Our main goal is to provide a suitable scientific platform to discuss all topics related to human death. Cubans, as hosts, will sincerely offer, a warm hospitality. This small Caribbean Island, with the greenness of its country and surrounded by an incredible blue sea, will be a suitable scenario to remind that any discussion about death is a reason for a better life.

We feel that any reason behind the efforts to enlarge our knowledge about human death (and life), is then.. just a matter of human dignity.

Prof. CALIXTO MACHADO, M.D., Ph.D.

President of the Organizing Committee

Tel.: (537) 327501 or 322233
Fax: (537) 22-8382 / 219496 / 218270
E.Mail: braind@infomed.sld.cu
Telex: 511609 palco cu
Stuart J. Youngner, M.D.
University Hospitals
Department of Medicine
11100 Euclid Ave.
Cleveland, Ohio 44106-6033
Telephone: 216-8443429
Fax 216-8443313
E.mail: sxy2@po.cwru.edu

MAIN TOPICS

Definitions of human death:
Brain death criteria in different countries and states :
Ancillary tests in brain death:
Pathological findings in brain death and related states :
Brain death in childhood and anencephalics
End-of-life dilemmas: persistent vegetative state, dementia, terminal patient, euthanasia, etc.:
Legal considerations on brain death and related states :
Bioethical considerations on brain death and related states :
Philosophical, theological, sociological, historical and cultural considerations on human death:
Brain death and organ transplantation

ORGANIZERS
Institute of Neurology & Neurosurgery of Havana.
(Director: Prof. SANTIAGO LUIS, M.D.):
International Conference Center

SPONSORS
International Association of Bioethics - Regional Program for Bioethics (Pan-American
Health Organization):
Quantified Neurophsysiology Belgian Group - Caribbean Organization for Brain Research (CARIBRO) - C.U.C.A.I.B.A (Center that coordinates organ and tissues
transplants in Buenos Aires Province, Argentina) - "Alfredo Thompson" Foundation for the Development of
Neuroscience (Argentina):
Ministry of Public Health:
National Commission for Brain Death Diagnosis - National Society for Neurosciences:
Cuban Society for Clinical Neurophysiology - Hermanos Ameijeiras Hospital:
Institute of Legal Medicine:
Institute of Nephrology:
Psychiatric Hospital of Havana:
"Calixto Garcia" Hospital


ORGANIZING COMMITTEE:
Dr. Calixto Machado, M.D., Ph.D. President
Dr. Orlando D. Garcia, M.D.
Dr. Jose M. Roman, M.D.
Cira Ramos
Mirna Farach
Dr. Alina Gonzalez, M.D.
Dr. Miguel A. Buergo, M.D.
Lic. Giovanni Romero
Dr. Luis Zarrabeitia, M.D.
Dr. Joel Gutierrez, M.D.
Dr. Miguel Farach, M.D.
Dr. Jorge Garcia-Tigera, M.D.
Dr. Rene Zamora, M.D.
Dr. L=DFzaro Vidal, M.D.

PRELIMINARY PROGRAM

 
DEFINITIONS OF HUMAN DEATH
Brain ontogenesis. The life and death of the human being and person. - Julius Korein (USA)
Death of the person or death of the organism? - Daniel Wikler (USA)
New controversies in the definition of death. - Stuart Youngner (USA)
A defense of the higher brain formulation of death. - Karein Gervais (CUBA)
Whole brain? Higher brain? A new formulation of death. - Orlando D. Garcia (CUBA)
A complete definition of death. - Bernard Gert (USA)
Somatic Integrative unity: A nonviable rationale for brain death - Alan Shewmon (USA)
Non-Heart beating cadavers and the definition of death - Robert Arnold (USA)
A new definition of death based on the basic mechanisms of consciousness generation in human beings. - Calixto Machado (CUBA)
CLINICAL APPROACH TO BRAIN DEATH AND RELATED ISSUES
The brain death state in medical science. - Katsuo Takeuchi and T. Shiogai (JAPAN)
Guidelines for the determination of death. - Calixto Machado and Orlando D. Garcia
Functional Neuroanatomy of the brainstem and its importance for the determination of death - J. M. Cuba (PERU)
Two standards of death in Denmark. - E.O. Jorgensen (Denmark)
Spinal man after brain death. - E.O. Jorgensen (Denmark)
The case of respirator brain after intracranium injury. - T. Sawaguchi (JAPAN)
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ANCILLARY TESTS IN BRAIN DEATH AND RELATED ISSUES
Neurophysiologic criteria from coma to brain death. - J. Paniagua-Soto, M. Pinero-Benitez and G. Vazquez-Mata (SPAIN)
Neurophysiological diagnosis of brain death. - Margarita Blanco (ARGENTINA)
Diagnostic reliability in loss of brainstem function evaluated by brainstem auditory evoked potentials and somatosensory evoked potentials in impending brain death. - T. Shiogai and K. Takeuchi (JAPAN)
Multimodality evoked potentials in the differential diagnosis of brain death. - J.M. Guerit, M. De Tourtchaninoff, P. Hantson and P. Mahieu (BELGIUM)
The problem of << brain death >> and organ donation in poisoned patients. - P. Hantson, P. Mahieu, M. De Tourtchaninoff, and J.M. GuThetarit (BELGIUM)
Role of the somatosensory evoked potentials in the diagnosis of brain death. - E. Facco, M. Murani, F. Baratto and G.P. Giron (ITALY)
A contribution of multimodality evoked potentials and electroretinography for the early diagnosis of brain death. - Calixto Machado (CUBA)
EEG in brain death diagnosis. - Enrique Delamonica (ARGENTINA)
Prolonged EEG activity in brainstem death. - A. Esteban, A. Traba, J. Prieto, R. Roldan and S. Santiago (SPAIN)
The low voltage EEG in coma. - W.T. Blume, D.K. McNeill, G.B. Young and P. Chiu (CANADA)
Accurate prediction of neurologic outcome after cardiac arrest. - Ted L. Rothstein (USA)
Study of intracranial circulation in brain-dead patients using transcranial doppler sonography (TCD)
J.M. Domonguez-Roldan and F. Murillo-Cabezas (SPAIN)
Scintigraphic Techniques in the Diagnosis and Confirmation of Brain Death. - H.P. Schlake, M. Scheubeck, R. Burger, Ch. Reiners, K. Roosen (GERMANY)
Heart rate variability in coma and brain death, - O. D. Garcia, C. Machado, J. M. Roman, A. Cabrera, L. Diaz- Comas, B. Rivera, R. Grave de Peralta (CUBA)
BRAIN DEATH IN CHILDREN AND RELATED ISSUES
Brain death determination in infants and children - S. Ashwal (USA)
The American Neurological Association anencephaly policy: Can medical speculations justify utilitarian homicide? - A. Shewmon (USA)
Consideration of anencephalic newborns as organ donors: Ethical problems related to the determination of death - E.R. Winkler (CANADA)
Withdrawal of life-support in pediatric critical care - D. D. Vernon (USA)
PERSISTENT VEGETATIVE STATE
The persistent vegetative state and the concept of person - Ra.l de Velasco (USA)
The vegetative state - C. M. DeGiorgio (USA)
The persistent vegetative state in infants and children - S. Ashwal (USA)
The German term "Apallic Syndrome" vs. the Anglo-American term "Persistent Vegetative State". - Th. Kallert (GERMANY)
Public policy and the persistent vegetative state. - William Winslade (USA)
Brain death and persistent vegetative state. Current debate in Italy - Carlo a. Defanti (ITALY)
Multimodality evoked potentials in the permanent vegetative state - J.M. GuThetarit (BELGIUM)
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BIOETHICAL, PHILOSOPHICAL, THEOLOGICAL, SOCIOLOGICAL AND CULTURAL CONSIDERATIONS IN BRAIN DEATH AND RELATED ISSUES
History of death - Carlo a. Defanti (ITALY)
Treating the quick and the dead: conflicts in biological constructs and the needs of a civil society. - Alta Charo (USA)
Redefining Death: Bioethical and Theological Implications - O. D. Garcoa and J. M. Rom=DFn (CUBA)
End-of-life care for non heart beating organ donors and their families - B. Spielman and C. Simmons - Brain death - The Indian Perspective - S. Jain and M.C. Maheshawar (INDIA)
Brain death: The Japanese controversy - E. A. Feldman (USA)
Brain death in Japan - Margaret Lock (USA)
Brain death, medical futility and other confusing concepts:Lessons in moral fallibility - Kenneth Goodman (USA)
Living organ donors - Steven Miles (USA)
Brain death and technological change - James J. Hughes (USA)
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END-OF-LIFE DILEMMAS
Euthanasia: a report from the Netherlands - J.K.M. Gevers (THE NETHERLANDS)
Euthanasia and its present debate in medicine - F.J. Leon (SPAIN)
Terminal Patient - Berta Serret (CUBA)
End-of-life decision facing brain death. Actual ethical- philosophical problems - Eduardo Fermin (CUBA)


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